Albumin, Normal Human Serum
Generic name
Albumin, Normal Human Serum
Trade name
Classification
PLASMA PROTEIN
Indication
Intravascular volume expansion, plasma exchange, maintenance of plasma colloid osmotic pressure.
Dosage form
20% w/v as 20 grams in 100 mL, 10 grams in 50 mL,
25% w/v as 25 grams in 100 mL, 12.5 grams in 50 mL,
5% w/v as 12.5 grams in 250 mL
Dose
Adult :
20% w/v solution: 2.5 to 5 mL/kg or 5% w/v solution : 10 to 20 mL/kg.
Child :
20% w/v solution: 2.5 to 5 mL/kg/dose (0.5 to 1 g/kg/dose) or 5% w/v solution : 10 to 20 mL/kg/dose (0.5 to 1 g/kg/dose).
The dose will depend on the patient’s clinical status. Maximum of 6 g/kg/24 h recommended
Administration
IV: Intermittent infusion
Intravenous Concentration
Intermittent Infusion
Intravenous Rate
Intermittent Infusion: 20% w/v solution: 1mL per minute. 5% w/v solution: 2 to 4 mL per minute
Storage
เก็บอุณหภูมิต่ำกว่า 25 C, ป้องกันแสง, ห้ามแช่แข็ง
Reconstitution
Not required.
Stability
ทิ้งหากตกตะกอนหรือขุ่น
Compatible fluid
NSS, D5W, Ringer’S
Incompatible fluid
vancomycin, verapamil
Incompatible drug
Adverse effect
Fluid overload, pulmonary oedema, fever, urticaria, flushing, increased prothrombin time, electrolyte disturbances, low platelet count
Precaution
Check for hypersensitivity to albumin before administration
Contraindication
