Atropine sulfate
Generic name
Atropine sulfate
Trade name
Classification
ANTI-MUSCARINIC AGENT
Indication
Vagolytic, bradycardia, premedication, adjunct in the treatment of organophosphate and carbamate poisoning.
Dosage form
0.6 mg/mL/ampoule
Dose
Adult :
Cardiac rhythm: Initially 0.5 to 0.6 mg, then incremental doses of 0.5 mg as needed IV or IM.
Maximum total dose of 2.5 mg in 2.5 ชั่วโมง
Pre-anaesthesia: 0.3 to 0.6 mg, IM or IV
Dose adjustment
Administration
IV: Bolus or Continuous infusion, IM, SC
Intravenous Concentration
Bolus: Undiluted or dilute 1 mL to 10mL,
Continuous Infusion: 0.1 to 1.2 mg per mL
Intravenous Rate
Bolus: Inject over 15 to 30 seconds.
Storage
เก็บอุณหภูมิต่ำกว่า 25 C, ป้องกันแสง
Reconstitution
Not required
Stability
Discard any unused solution
Compatible fluid
NSS, D5W
Incompatible fluid
Incompatible drug
adrenaline, ampicillin, amylobarbitone, chloramphenicol, flucloxacillin, heparin, metaraminol, methicillin, noradrenaline, promazine, sodium bicarbonate, sodium iodide, tetracycline, thiopentone, vitamin B group with ascorbic acid
Adverse effect
Hypersensitivity reactions, dry nose or mouth, flushing, urinary retention, mydriasis, photophobia, rash, blurred vision, paradoxical bradycardia (low doses), tachycardia, reduced perspiration, confusion, coma, tachypnoea
Precaution
Contraindication
Information
