Calcium folinate Folinic acid
Generic name
Calcium folinate Folinic acid
Trade name
Calcium leucovorin®
Classification
ANTIDOTE
Indication
Megaloblastic and macrocytic anaemias resulting from folate deficiency, antidote to folic acid antagonists, and adjunct to fluorouracil
Dosage form
50 mg in 5mL/vial.
Dose
Dose adjustment
Administration
IV: Bolus, Intermittent infusion, continous infusion, IM
Intravenous Concentration
Bolus: 50 mg in 5 mL.
Intermittent Infusion: The required dose in 100 mL.
Continuous Infusion: The required dose in 1000 mL.
Intravenous Rate
Bolus: Inject over 3 to 5 minutes. Not to exceed 160mg per minute.
Intermittent Infusion: Infuse over 1 to 4 hours.
Continuous Infusion: Infuse over 6 to 12 hours.
Storage
Store at 5 ° C. ป้องกันแสง
Reconstitution
Not required.
Stability
Contains no bacteriostat. Discard any unused solution.
Compatible fluid
NS; D5W
Incompatible fluid
Incompatible drug
fluorouracil, foscarnet, sodium bicarbonate
Adverse effect
Precaution
Contraindication
Information
