Cefazolin
Generic name
Cefazolin
Trade name
Fazolin®
Classification
ANTI-INFECTIVE ANTIBACTERIAL CEPHALOSPORIN First Generation
Indication
Sensitive bacterial infections including gram-positive and some gram-negative organisms.
Dosage form
1 gram/vial
Dose
Adult: 500 mg to 1 gram every 6 to 8 hours.
Up to 6 grams can be given daily in severe infections.
Child: Initial dose 20 mg/kg, then 10mg/kg/dose every 6 hours
Dose adjustment
Administration
IV: Bolus, Intermittent infusion, continous infusion, IM
Intravenous Concentration
Bolus: 500 mg to 1 gram per 10mL.
Intermittent Infusion: 500 mg to 1 gram in 50 to 100 mL.
Continuous Infusion: Dilute the required dose in 50 to 1000 mL.
Intravenous Rate
Bolus: 2 mL per minute.
Intermittent Infusion: Infuse over 10 to 60 minutes.
Continuous Infusion: Infuse over 8 to 24 hours.
Storage
Store below 25 ° C. ป้องกันแสง
Reconstitution
WFI 10 mL per gram.
Stability
Stable for 10 วัน at 5 ° C and 24 hours at 25 ° C.
Compatible fluid
NS; D5W
Incompatible fluid
Incompatible drug
amikacin, amiodarone, ascorbic acid, atracurium, bleomycin, calcium, cimetidine, colistin, erythromycin, lignocaine, polymyxin, ranitidine, rocuronium, tetracycline, vitamin B group with ascorbic acid
Adverse effect
Precaution
Contraindication
Information
