Penicillin G
Generic name
Benzylpenicillin Penicillin G
Trade name
Classification
ANTI-INFECTIVE ANTIBACTERIAL PENICILLIN
Indication
Sensitive bacterial infections including gram-positive and some gram-negative organisms.
Dosage form
5 million units (3 g)/vial
Dose
Adult: 500,000 units to 1 million units every 4 to 6 hours.
Maximum: 20 million units daily.
Child: 50,000 units/kg/dose every 4 to 6 hours. Maximum: 500,000 units/kg/24 h.
Dose adjustment
Administration
IV: Bolus, Intermittent infusion, continous infusion, IM
Intravenous Concentration
Bolus: 1 million units (600mg) per 10mL
Intermittent Infusion: 1 to 5 million units per 50 to 100mL
Continuous Infusion: Dilute the required dose in 1000 to 2000mL
Intravenous Rate
Bolus: 5 mL per minute.
Maximum 500,000 units per minute.
Intermittent Infusion: Infuse over 15 to 30 minutes.
Continuous Infusion: Infuse over 24 hours.
Storage
Store below 25 ° C. ป้องกันแสง
Reconstitution
WFI 10 mL per gram.
Stability
Stable for 7 วัน at 5 ° C and 24 hours at 25 ° C.
Compatible fluid
NS; D5W
Incompatible fluid
Fat emulsion 10% w/v
Incompatible drug
amikacin, amphotericin, cephalothin, chlorpromazine, ciprofloxacin, dopamine, flucloxacillin, gentamicin, heparin, lincomycin, metaraminol, metoclopramide, prochlorperazine, promazine, promethazine, sodium bicarbonate, thiopentone, tetracycline
Adverse effect
Precaution
Contraindication
Information
